Advanced Prostate Cancer

Advanced Prostate Cancer/

Weekend And July Hospitalizations Worsen Outcomes for Metastatic Prostate Cancer Survivors

Oh, those weekends, don’t you just love them? They provide us with an opportunity to spend time with our families, drive to the country house or go to the theater. Now, we know they also provide us with an increased opportunity to die in a hospital. Research shows that men with metastatic prostate cancer who are admitted to a hospital on a weekend are more likely to die and suffer complications compared with those admitted on weekdays!

The research, which was led by Marianne Schmid, MD, of Harvard Medical School, used the National Inpatient Sample to identify 534,011 hospitalized men with […]

By |July 2nd, 2015|General Information, survivorship, Uncategorized|0 Comments

An Additional Explanation Of The Proposed ASCO Drug Rating System

One of my prior posts (http://advancedprostatecancer.net/wp-admin/post.php?post=5349&action=edit)  explained the current movement to establish a rating system that a prostate cancer survivor, along with their doctor, could use to make better decisions about which drugs to use.  The rating system, or formula, factors in information about efficacy (additional survival time), side effects, safety of the drug, and symptom control.

I have received a number of questions asking me to expand upon the proposed formula.  So, here it is:

The efficacy portion of ASCO’s rating accounts for up to 80 points of the score. ASCO also awards up to 20 points based on how safe […]

Describing My Experience Being Diagnosed With A Fifth Cancer – A Video To Watch

I attend the American Society of Clinical Oncology (ASCO) meeting in Chicago in May.  As usual, it was exciting and it provides me with a fantastic opportunity to catch up with the current research in advanced prostate cancer.  It also gives me an opportunity to meet with and have private conversations with some of the greatest researchers in prostate cancer.

In addition I am occasionally asked to share a survivor perspective to the meeting.  Over the last few meetings I have also made some videos with Patient Power.  At this last meeting I made a video about my experience having been […]

On Hormone Therapy – To Statin Or Not, That Is The Question

JAMA Oncology has published a new study that suggests that adding a statin drug at the initiation of hormone therapy (ADT) to the treatment protocol for a man with progressive, hormone-sensitive prostate cancer may significantly impact their actual time to disease progression (TTP).

Historically, we know Statin use has been associated with improved prostate cancer outcomes. It is believed that the biology behind the positive effect of statin drugs is directly related to the fact that Dehydroepiandrosterone sulfate (DHEAS) is a precursor of testosterone (which feeds prostate cancer) and a substrate for SLCO2B1, an organic anionic transporter (moving substances into the […]