Advanced Prostate Cancer

Advanced Prostate Cancer/

Enzalutamide Is Good For Older Patients With Metastatic Castration-Resistant Prostate Cancer

Once a clinical trial has been completed, especially when the trial is positive, researchers will “data mine” the published information. The published results provide additional opportunities to evaluate the data in different ways than the trial was originally designed. This new data can be very interesting and informative, however it also needs to be considered somewhat suspect since the trial was not initially designed to answer these additional questions.

We do know that prostate cancer disproportionately affects older men and a man’s age should affect treatment decisions. So, it is important to understand the efficacy and tolerability of the therapies used […]

Not All Men Benefit From Radium-223 (Xofigo)?

Researchers are now beginning to understand which men with castration-resistant prostate cancer (CRPC) might be helped by radium-223 (Xofigo), and for which men Xofigo will be a waste of time and money, and possibly cause harm.

They have found that baseline ECOG performance status, alkaline phosphatase (ALP), hemoglobin (Hb) levels, and the concomitant use of abiraterone acetate (Zytiga) or denosumab were indicators for improved overall survival (OS) when radium-223 is used. These findings came from a phase IIIb follow-up to the pivotal phase III ALSYMPCA trial presented at the 7th European Multidisciplinary Meeting on Urological Cancers (EMUC).

Data from the post-hoc analysis showed an improved […]

Why A Diet Heavy in Fruits and Vegetables Might Help Men With Prostate Cancer

Many people consider food diet important in both prostate cancer prevention and in controlling its progression. Dietary derived agents, such as the flavonoids derived from fruits and vegetables should be of particular interest for prostate cancer survivors, as they seem to offer both chemo-prevention and an antioxidant effect along with a favorable safety and side-effect profile.

Flavonoids that are directly derived from fruits and vegetables demonstrate an action on the androgen receptor (AR) axis thus having a particular value for preventing or treating castrate-resistant prostate cancer.

There are four main flavonols – quercetin, myricetin, kaempferol, and fisetin that have been demonstrated in […]

Payment for PSA Prostate Cancer Screening may end

Believe it or not, in this week approaching Thanksgiving, we in the United States are faced with a second challenge to Prostate Cancer screening using the PSA test. Malecare wants you to know.
The Centers for Medicare and Medicaid Services (CMS) is asking for pubic comment on a clinical quality measure that would probably lead to financial penalties for providers (your doctor) who order a PSA screening test. The measure is based on the PSA screening recommendations of the U.S. Preventative Services Task Force (USPSTF).
The USPSTF is the organization responsible for the recommendation against prostate cancer screening. Their May 2012 recommendation […]

By |November 15th, 2015|advocacy|0 Comments