Comments on: The Prostate Cancer Community Reaffirms their Support for Provenge http://advancedprostatecancer.net/?p=31 Sharing experiences, support and advice for men with advanced & recurrent Prostate Cancer Tue, 07 Sep 2010 11:59:15 +0000 http://wordpress.org/?v=2.9.2 hourly 1 By: Joel http://advancedprostatecancer.net/?p=31&cpage=1#comment-89 Joel Mon, 21 May 2007 20:20:11 +0000 http://advancedprostatecancer.net/?p=31#comment-89 Don, As of this moment Provenge is not available to anyone, other then through their on-going clinical trial, as the FDA failed to approve the treatment. The FDA has requested additional data about its efficacy and about their manufacturing process. The approval that has been requested is for HR prostate cancer where the survivor does not have symptoms. If it were approved then it might be possible to have your doctor write an off label prescription. I am not aware of any research where Provenge has been used after chemo. Dr. Daniel Petrylak has conducted a study where Provenge was used before chemo. He found a significant increase in life extension. Joel Don, As of this moment Provenge is not available to anyone, other then through their on-going clinical trial, as the FDA failed to approve the treatment. The FDA has requested additional data about its efficacy and about their manufacturing process.

The approval that has been requested is for HR prostate cancer where the survivor does not have symptoms. If it were approved then it might be possible to have your doctor write an off label prescription.

I am not aware of any research where Provenge has been used after chemo. Dr. Daniel Petrylak has conducted a study where Provenge was used before chemo. He found a significant increase in life extension.
Joel

]]> By: Don Cornett http://advancedprostatecancer.net/?p=31&cpage=1#comment-86 Don Cornett Mon, 21 May 2007 16:06:32 +0000 http://advancedprostatecancer.net/?p=31#comment-86 I am at metastatic bone cancer due to advanced prostate cancer which had invaded the prostate wall 9 yrs ago. I have had chemo, radiation, Lupron, Taxotare, and any other treatment available at Moffitt Cancer Center. What is the chance of this new treatment working for me now? Any one with a solid answer? I am at metastatic bone cancer due to advanced prostate cancer which had invaded the prostate wall 9 yrs ago. I have had chemo, radiation, Lupron, Taxotare, and any other treatment available at Moffitt Cancer Center. What is the chance of this new treatment working for me now? Any one with a solid answer?

]]> By: Michael Diegel http://advancedprostatecancer.net/?p=31&cpage=1#comment-57 Michael Diegel Sun, 06 May 2007 22:35:55 +0000 http://advancedprostatecancer.net/?p=31#comment-57 I have worked in the cell cancer therapy field for more than 5 years. Dendritic cell therapy has great potential as evidenced by Dendreon's "Provenge". However, what Dendreon has accomplished is only the beginning. Minor modification of Dendreon's stategy has the capability of curing many thousands of cancer patients (prostate, breast, and renal). Let us all hope and pray for a positive recommendation from the FDA so that this novel therapy may be fully developed to reach it's full potential and revolutionize cancer therapy. I have worked in the cell cancer therapy field for more than 5 years. Dendritic cell therapy has great potential as evidenced by Dendreon’s “Provenge”. However, what Dendreon has accomplished is only the beginning. Minor modification of Dendreon’s stategy has the capability of curing many thousands of cancer patients (prostate, breast, and renal). Let us all hope and pray for a positive recommendation from the FDA so that this novel therapy may be fully developed to reach it’s full potential and revolutionize cancer therapy.

]]> By: Steve http://advancedprostatecancer.net/?p=31&cpage=1#comment-56 Steve Sun, 06 May 2007 22:08:09 +0000 http://advancedprostatecancer.net/?p=31#comment-56 What Provenge has shown is truly remarkable results for late stage prostate cancer. Very minimal side effects and a 300% increased chance for 3 year survival, when most men with HRPC don't live more than 20 months after hormone treatments fail to continue working. Provenge absolutely needs to be approved right away, and I hope dearly it will be shown effective in early stage PC as well. This is exactly the kind of therapy the drug industry need to be working on. Not more chemos but active immunotherapies. They are now shown to work well, so lets get more of them into study and into the market. The FDA will make a powerful, positive statement by approving Provenge. Money will flow into new areas of research and that is exactly what we need. I hope the FDA understands how important this is. It is important for PC patients and it is important for the advancement of medical sciences in general. What Provenge has shown is truly remarkable results for late stage prostate cancer. Very minimal side effects and a 300% increased chance for 3 year survival, when most men with HRPC don’t live more than 20 months after hormone treatments fail to continue working.

Provenge absolutely needs to be approved right away, and I hope dearly it will be shown effective in early stage PC as well. This is exactly the kind of therapy the drug industry need to be working on. Not more chemos but active immunotherapies. They are now shown to work well, so lets get more of them into study and into the market.

The FDA will make a powerful, positive statement by approving Provenge. Money will flow into new areas of research and that is exactly what we need. I hope the FDA understands how important this is. It is important for PC patients and it is important for the advancement of medical sciences in general.

]]> By: John W Stevenson http://advancedprostatecancer.net/?p=31&cpage=1#comment-54 John W Stevenson Sun, 06 May 2007 21:45:03 +0000 http://advancedprostatecancer.net/?p=31#comment-54 If the Government cleaned house at the SEC and canned the bunch of them and brought some new blood, it would be honest for a while anyway. Provenge--36 out of 100 still alive after 36 months Placebo-- 11 out of 100 still alive after 36 months Provenge and Taxotere combo 15 months longer average survival longer than Taxotere alone. And, Taxotere the only other treatment. If this Provenge is not approved and Manipulated off the board by big money---well what can a decent human say. If the Government cleaned house at the SEC and canned the bunch of them and brought some new blood, it would be honest for a while anyway.

Provenge–36 out of 100 still alive after 36 months
Placebo– 11 out of 100 still alive after 36 months

Provenge and Taxotere combo 15 months longer average survival longer than Taxotere alone. And, Taxotere the only other treatment.

If this Provenge is not approved and Manipulated off the board by big money—well what can a decent human say.

]]> By: Burleigh Grimes http://advancedprostatecancer.net/?p=31&cpage=1#comment-53 Burleigh Grimes Sun, 06 May 2007 21:43:01 +0000 http://advancedprostatecancer.net/?p=31#comment-53 I feel provenge is a much better treatment for advanced protate cancer than anything out there today.I am for one hundred percent full approval without delay. I feel provenge is a much better treatment for advanced protate cancer than anything out there today.I am for one hundred percent full approval without delay.

]]> By: Gates http://advancedprostatecancer.net/?p=31&cpage=1#comment-52 Gates Sun, 06 May 2007 17:22:17 +0000 http://advancedprostatecancer.net/?p=31#comment-52 The number of hedge funds who have attempted to grind this company into the ground for profit motives alone has sickened me. This kind of amoral behavior is beyond belief. What's even worse is that they have continued with their amoral and illegal practices even after data was realeased showing what a huge step Provenge was in the attempt to fight cancer. More patient groups need to come forward and voice their support for Provenge and do so quickly before any more damage is done by those whose motivations are less than honorable. It is difficult to believe that the SEC has been nothing more than a passive witness while large hedge funds break laws the SEC is sworn to uphold. Calls to your congressional representatives are needed desparately. The number of hedge funds who have attempted to grind this company into the ground for profit motives alone has sickened me. This kind of amoral behavior is beyond belief.

What’s even worse is that they have continued with their amoral and illegal practices even after data was realeased showing what a huge step Provenge was in the attempt to fight cancer.

More patient groups need to come forward and voice their support for Provenge and do so quickly before any more damage is done by those whose motivations are less than honorable.

It is difficult to believe that the SEC has been nothing more than a passive witness while large hedge funds break laws the SEC is sworn to uphold. Calls to your congressional representatives are needed desparately.

]]> By: Robert Desjardins http://advancedprostatecancer.net/?p=31&cpage=1#comment-50 Robert Desjardins Sun, 06 May 2007 14:39:55 +0000 http://advancedprostatecancer.net/?p=31#comment-50 My wife and I live in a retirement community that has many prostate cancer victims who desperately need Provenge to give them hope for extended longevity. Nice work. My wife and I live in a retirement community that has many prostate cancer victims who desperately need Provenge to give them hope for extended longevity. Nice work.

]]> By: L. E. Arnold http://advancedprostatecancer.net/?p=31&cpage=1#comment-49 L. E. Arnold Sun, 06 May 2007 13:29:00 +0000 http://advancedprostatecancer.net/?p=31#comment-49 Me, my son, my brothers and men all around the world are 100% behind this effort! WE NEED A BETTER CHOICE!! Me, my son, my brothers and men all around the world are 100% behind this effort!

WE NEED A BETTER CHOICE!!

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