Clinical Trials & Research

/Clinical Trials & Research

Men Who Fail Primary Radiation Can Have Good Results After Salvage Surgery

Men who have decided to have radiation as their first (primary) treatment for prostate cancer have a one-third chance of recurrence. Some of those men have salvage radical prostatectomy (SRP)  to fight the recurrence.  A study shows this might be a good idea. Antoni Vilaseca, MD, etal from Memorial Sloan-Kettering Cancer Center in New York, studied 251 men who had a Salvage Radical Prostatectomy (SRP) after they failed their primary treatment with external beam radiation therapy, brachytherapy (seeds), or with both. The researchers evaluated long-term oncologic outcomes (survival and disease progression) of the SRP in general as well as evaluating if using minimally [...]

Cancer Diagnosis Causes Increased Emotional Problems for Too Many of Us

Being diagnosed with cancer is tough. Being diagnosed with cancer is often coupled with clinically meaningful levels of mental or emotional distress. Researchers in Germany have found that during the prior four weeks nearly a third of more than 2,100 cancer survivors interviewed at inpatient and outpatient care centers experienced mental or emotional distress that meets the strict diagnostic criteria for mental disorders including anxiety, depressive and adjustment disorders. In the normal, non-cancer survivor population we would not expect to see rates higher than 18% at most. When the researchers evaluated the types of disorders they found that 11.5% of [...]

By | December 23rd, 2016|General Information, How We Live, mental health, Research, Uncategorized|0 Comments

New Investigational Treatment Instead of Active Surveillance & Maybe for Distant Tumors

Today’s post is not directly an advanced prostate cancer post, but more about a new potential and very interesting treatment on the horizon for men with prostate cancer that might otherwise be considered for active surveillance. According to the researchers who have been working on the treatment protocol, it is "truly transformative". This is not a treatment that is yet ready for prime time, but it is a possible treatment that, if proven, could be transformative for many men yet to be diagnosed. This new approach to treating early, non-aggressive prostate cancer has been tested across Europe. It involves the [...]

By | December 20th, 2016|Clinical Trials, Drugs & Treatments, Lasers|0 Comments

Xtandi In Combination with Zytiga Is Not Better Than Either Drug Alone

Often I have heard people ask why if one drug is effective we shouldn’t simply take two or three at the same time? The answer is simple, because we don’t know if combining multiple drugs will make any difference to a man’s survival. The only way we can be sure is with good evidence. Good evidence requires, in the case of drugs, doing a clinical trial to see if a certain type of combination will be beneficial. In such a late-stage clinical trial designed to see if Xtandi in addition to Zytiga along with a steroid worked any better than [...]

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