Peripheral neuropathy caused by chemotherapy is a very common problem for many of us as we go through a chemotherapy regime. Despite the large numbers of us who do suffer from this side effect there has been limited numbers of doctor suggested remedies. On the Malecare/ HealthUnlocked Advanced Prostate Cancer online support group there was a recent post from one of the members about a suggestion he has received from his doctor to combat this problematic side effect. The recommendation was to use Pyridoxine 100mg (Vitamin B 6) twice a day and Alpha Lipoic Sustained release 300mg twice a day [...]
The following was written and posted by Paul Edwards to the Advanced Prostate Cancer Online Support Group: The March 2014 issue of the Asia-Pacific Journal of Clinical Oncology published an article “Why do some cancer patients receiving chemotherapy choose to take complementary and alternative medicines and what are the risks?” by authors from University of Queensland School of Pharmacy and the Sunshine Coast Cancer Care Services. The research found that Complementary and alternative medicine (CAM) that is systemically absorbed is most likely to interfere with concurrent chemotherapy and potentially cause harm to cancer patients. When tested in rigorous clinical trials, no [...]
Startling Fact: PSA Testing Frequency Changes PSA Doubling Time – A Time Honored Surrogate Biomarker is Not Valid!
In our quest to understand our prostate cancer we have developed many “measures” of our disease aggressiveness and progression. Many of these measures are generally accepted has valid, but many have never been validated. One example is the prognostic nature of PSA Doubling Time (PSADT) in men with biochemically recurrent prostate cancer (BRPC or PSA only increases with negative scans). PSADT is used as common intermediate endpoint for assessing the efficacy of therapies. A number of investigational agents appear to favorably effect PSADT, slowing of PSADT has also been observed in placebo-treated men. Researchers from Johns Hopkins Hospital theorized that [...]