Disease Progression

/Disease Progression

Men Who Fail Primary Radiation Can Have Good Results After Salvage Surgery

Men who have decided to have radiation as their first (primary) treatment for prostate cancer have a one-third chance of recurrence. Some of those men have salvage radical prostatectomy (SRP)  to fight the recurrence.  A study shows this might be a good idea. Antoni Vilaseca, MD, etal from Memorial Sloan-Kettering Cancer Center in New York, studied 251 men who had a Salvage Radical Prostatectomy (SRP) after they failed their primary treatment with external beam radiation therapy, brachytherapy (seeds), or with both. The researchers evaluated long-term oncologic outcomes (survival and disease progression) of the SRP in general as well as evaluating if using minimally [...]

The 5 Important Questions We Need To Ask Men Who Are End Stage – Handling Grief

Advanced prostate cancer will eventually end, barring another cause of death, with the demise of the individual survivor. Knowing that you suffer from a terminal illness is hard, it is hard on the family and it is hard on the individual. Many of us don’t think about it, but it is also hard for many of our healthcare professionals. We all have great difficulty dealing with the thought of the eventual and then the actual death of our loved one. In many cases this difficulty also extends to our healthcare professionals. Like the family, they need to find a way [...]

Efficacy of Enzalutamide in Castrate-Resistant Prostate Cancer in Men with Visceral Metastases

We know that men with metastatic castration-resistant prostate cancer (mCRPC) and visceral metastases have a worse prognosis than those with non-visceral metastases. The important question we need to understand is what, of our currently available treatments, might be effective for this more aggressive and deadly type of prostate cancer? Results of the phase 3 AFFIRM clinical trial have demonstrated that treatment with the androgen receptor inhibitor enzalutamide (Xtandi) resulted in significant improvements in outcomes for men with mCRPC. This blog post discusses the efficacy of enzalutamide among men from the AFFIRM trial who had visceral disease. Men who were in [...]

To Debulk Or Not To Debulk, That Is The Question

You have been diagnosed with advanced or metastatic prostate cancer. It is a shock, you have cancer and your cancer has already spread outside of the prostate gland. Your doctor might have already told you that at this stage it is no longer curable, and technically it can be called terminal! That is a lot of stuff that has been just pushed on to your plate. Theoretically, this is correct, but for many of us, despite having this diagnosis, we will not die from the prostate cancer! Treatment today allows us to delay the cancer long enough that we will [...]

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