Some Tricks To Help You Maintain Adequate Nutrition When On Chemotherapy

Having chemotherapy causes all sorts of strains and difficulties. One almost universal side effect from chemotherapy is the difficulty many of us face in getting enough nutrition. Nutrition comes from eating food yet many of us just don't feel hungry so eating is difficult. We lose our appetite, food tastes terrible and we battle nausea. However, there are a few different things you can do to better manage your eating while on Chemotherapy. 1- At the times it is difficult to eat, don’t push it. Instead, drink a liquid or a powdered meal replacement. 2- It is easier to eat [...]

Our New Therapies and the Development of Cross Resistance to these Drugs

Men with metastatic castrate resistant prostate cancer (mCRPC) have become fortunate over the last few years as there we now have a number of new drugs available which can extend our life and can also have some palliative effects. However, as we have more treatments being approved, we find that we are faced with a significant issue, how to sequence these drugs. The major problem causing this sequencing crisis is cross-resistance. The use of each of any of these drugs limits the use of the another drug in men who have failed the original prior therapy. This problem, cross-resistance, is [...]

Combination Chemotherapy Treatments Maybe More Effective Than Each Drug In Sequence

According to a news release from MD Anderson they have recently completed a study that shows that combining two separate chemotherapy agents is more effective than sequencing them one after another. The current standard of care for the cytotoxic chemotherapy agents used to treat prostate cancer is to treat men with advanced metastatic castration-resistant prostate cancer (mCRPC) by the sequential use of single agent taxanes such as docetaxel and cabazitaxel. Usually, docetaxel is used as the “first-line” therapy while cabazitaxel is used as the “second-line” therapy. The use of these therapies as a combination therapy at the same time has [...]

Evaluating The Side Effects Of Docetaxel (Taxotere) vs Cabazitaxel (Jevtana)

Many men express great hesitation to move to chemotherapy with both docetaxel (taxotere) and cabazitaxel (Jevtana) because of the side effects which can include alopecia (hair loss), nail changes, neuropathy, and dysgeusia (a distortion of the sense of taste). A group of researchers hypothesized that the adverse side effects (AE) of these two chemotherapy drugs, cabazitaxel and docetaxel would be different. To compare the AEs they prospectively collected data on treatment side effects reported from the clinical trial databases of docetaxel every 3 weeks (q3w) (in TAX327 and VENICE) and cabazitaxel q3w (in TROPIC). They found that the frequency of [...]

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