Possible Protocols To Treat Chemotherapy Induced Peripheral Neuropathy

Peripheral neuropathy caused by chemotherapy is a very common problem for many of us as we go through a chemotherapy regime. Despite the large numbers of us who do suffer from this side effect there has been limited numbers of doctor suggested remedies. On the Malecare/ HealthUnlocked Advanced Prostate Cancer online support group there was a recent post from one of the members about a suggestion he has received from his doctor to combat this problematic side effect. The recommendation was to use Pyridoxine 100mg (Vitamin B 6) twice a day and Alpha Lipoic Sustained release 300mg twice a day [...]

Combination Chemotherapy Treatments Maybe More Effective Than Each Drug In Sequence

According to a news release from MD Anderson they have recently completed a study that shows that combining two separate chemotherapy agents is more effective than sequencing them one after another. The current standard of care for the cytotoxic chemotherapy agents used to treat prostate cancer is to treat men with advanced metastatic castration-resistant prostate cancer (mCRPC) by the sequential use of single agent taxanes such as docetaxel and cabazitaxel. Usually, docetaxel is used as the “first-line” therapy while cabazitaxel is used as the “second-line” therapy. The use of these therapies as a combination therapy at the same time has [...]

Dr. Mark Scholz Discusses Treatment Issues For Advanced Prostate Cancer

At the recent 2011 Prostate Cancer Research Institute Dr. Mark Scholz discussed care issues for men with advanced metastatic prostate cancer. In his presentation he stressed the importance of closely monitoring each man’s individual, on-going response to treatment to determine its effectiveness. He made a case that without close monitoring; treatment decisions would lag behind disease state. Dr. Scholz said that he believes that it is important to change treatments after 60-90 days if there hasn’t been an adequate response, or if there are excessive side effects. He suggested the following monitoring benchmarks: • Changes in pain • Checking PSA, [...]

Carboplatin – A 2nd line chemotherapy?

Carboplatin is a chemotherapy agent used for treatment of many types of cancer. Currently, it is approved by the Food & Drug Administration (FDA) for treating patients with ovarian and non-small cell lung cancer. However, some oncologists use carboplatin “off-label” for other cancers. Commonly, these “off-label” uses include testicular, stomach, and bladder cancers as well as other carcinomas. Some doctors are examining the efficacy of carboplatin as a second line chemotherapy agent (after the failure of taxotere) as well as along with taxotere therapy for men with advanced prostate cancer. Some web sites about the use of carboplatin with and after taxotere are: […]