Hormone Therapy

//Hormone Therapy

Is Alkaline Phosphatase A Bio-Marker To Predict PSA Decline And Clinical Benefit From Abiraterone Acetate in Bone Metastatic Castration Resistant Prostate Cancer

Again and again I have mentioned the huge need we have for the development of reliable bio-markers. Reliable bio-markers will allow us to know which men will respond positively to a treatment (also those who will not) and when a treatment is still effective (also when it no longer is effective). These biomarkers really don’t exist, so a lot of clinical decision-making is based upon the experience and gut feeling of our doctors. This type of decision-making is not adequate in today’s world of multiple treatment options, especially when many of the treatments can foster resistance to other available treatments. [...]

Some Factors That Might Be Predictors of the Duration of Abiraterone Acetate in Men with Castration-Resistant Prostate Cancer

Being able to make better decisions about drug sequencing and combinations has become one of the current hot topics in prostate cancer research. Given that we have a number of newer drugs to use this is an important clinical issue as we make important treatment decisions. Making these clinical decisions is tough.  The fact is that prostate cancer is a very heterogeneous disease and so  drug  responses are not consistent. Compounded by the fact that none of our treatments are effective for an extended time period knowing how to accurately predict drug response is vital. One  example of research dealing [...]

CVS Removes Xtandi From Its Formulary List – They Will Not Pay!

CVS Health, a major retail pharmaceutical insurer and supplier has raised some consternation and concerns and it should also raise yours. Last Tuesday, CVS rolled out their 2017 formulary list that left off the some of the world’s top-selling drugs including a vital castrate resistant prostate cancer drug. The pharmacy benefits manager removed from their list Medivation and Astellas' prostate cancer treatment, Xtandi. They argued that Johnson & Johnson’s Zytiga is also a hormone therapy drug (and is cheaper than Xtandi) could be used in its place. This is a problem as they are not the same drug. Their modes [...]

Hormone Therapy (ADT) for Prostate Cancer Patients Might Provide Us Another Long Term Gift – Alzheimer’s Disease

Hormone therapy (ADT) is notorious for providing us with side effects. Some of these side effects are best described as ones that deteriorate our general quality of life. For example the most common one we all are familiar with is, of course, hot flashes. You could also add erectile dysfunction as well as loss of sexual desire to these common side effects. In most cases, if you are on intermittent therapy, when you move into an off period you will experience a period of side effect abetment, at least until you go back onto therapy. We also know that ADT [...]

By | July 14th, 2016|ADT, Drugs & Treatments, Hormone Therapy, Uncategorized|0 Comments
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