How To Have A Firmagon Injection And Minimized The Side Effects

Three of the participants on the Malecare Health Unlocked Advanced Prostate Cancer Online Support Group have been sharing their personal experiences and recommendations on how to best get a Firmagon injection. It is clear that how the injection is given has a direct effect on he pain and inflammation a man will experience from the injection. If you are getting ready to start Firmagon you should heed these recommendations. Dave 2 said, “My experience w/ Firmagon was similar to yours--initial doses to stomach area but at too shallow an angle. This med is very dependent on skill of nurse administering [...]

An Evaluation of Testosterone Flare During a Transition from Degarelix to Leuprolide in Men on ADT *

Many men with advanced prostate cancer who are on hormone therapy (ADT) use one of the newer drugs, degarelix (Firmagon) to achieve a state of castration. Degarelix is considered a superior drug for initiating ADT because it is not accompanied with a PSA flare that is common with the older luteinizing hormone-releasing hormone (LHRH) agonists and LHRH antagonists. Degarelix is more expensive than these other drugs and it is very common for men to be switched from degarelix to one of the other dugs. But, what happens when a man is switched? Given the large number of men who are [...]

Degarelix Monotherapy vs. Luteinizing Hormone-Releasing Hormone Agonists Plus Antiandrogen Flare Protection For Men With Advanced Prostate Cancer *

There are a number of different flavors of hormone therapy (ADT) used to treat advanced prostate cancer. However, they could be summed up and put into two different categories. 1- The use of luteinizing hormone-releasing hormone (LHRH) agonist therapy (drugs like Lupron and Zoladex) along with short term antiandrogen (AA) flare protection 2- Degarelix, a gonadotrophin-releasing hormone antagonist which does not require the use an antiandrogen (AA) flare protection drug because it does not cause a surge in testosterone levels. In a research study where individual patient data from two phase III trials had been pooled to compare the one [...]

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