Vitamin D3 Potentiates Metformin in DU145 Human Prostate Cancer Cells

It is well established that common drugs like Metformin and vitamin D? exhibit a strong anti-proliferative action in many cancer cell lines. Recent research confirms that this is also true in human prostate cancer cells. In a recent study it was demonstrated that the combination of the two drugs, metformin and vitamin D3, had a much stronger positive effect on DU145 human prostate cancer cell growth than either drug alone. These two drugs showed a synergistic effect on cell proliferation and apoptosis. Most of us do not know the genetic structure of our cancer tumor, so we do not know [...]