Radiation

Expanding the Role of Radium-223 (Xofigo)

One of the newer drugs and one that has recently had great air play is the bone targeting radiopharmaceutical drug radium-223 or Xofigo. Currently, it is approved for men with castrate resistant prostate cancer with bone metastases. The problem is that currently Xofigo is only approved for one round of treatment using 6 monthly infusions. Given its success, the question we are now asking is if additional dosing would provide an even better result? Bayer Pharmaceuticals currently has a number of clinical trials examining this type of question. In one of the small prospective studies looking at the impact of [...]

A Brief Update of the Current Landscape of Bone Targeted Therapies for Prostate Cancer

Prostate cancer tends to metastasize to bones as opposed to soft tissue and other organs.   We have no idea why it does have a preference for bone, but it does. Developing bone metastases in prostrate cancer is a very strong negative prognostic indicator. Prostate cancer’s tendency to favor bone over soft tissue causes significant morbidity and mortality for men. Bone metastasis has a major impact on quality of life and longevity for men with prostate cancer and it needs to be aggressively treated. Because of this, prostate cancer survivors need to focus on drugs that slow down or interfere with [...]

Prior Radiation Exposure Should Not Effect The Outcomes Derived From The Implantation Of An Artificial Urinary Sphincter

The possibility of having incontinence as a side effect from all of the primary prostate cancer treatments is significant. Incontinence is not an either or thing as the degree of incontinence varies from individual to individual. Those men having significant levels of inconvenience find that their quality of life is significantly damaged in some cases to the point that we are unable to live our life. We cannot go to the theater, take an airplane, meet friends or family outside our own home, etc.  Life becomes difficult and unhappy. The most common procedure to combat this level of incontinence is [...]

Radiotherapy Might Not Extend Survival In Men With Prostate Cancer Who Are Under 70 Years Old

Increasingly, we are seeing younger men diagnosed with prostate cancer and with bone metastases. One of the more common therapies, radiotherapy is recognized for its effect on local control of bone metastases, but whether it could prolong overall survival, the gold standard is still controversial. Researchers retrospectively evaluated 113 men with prostate cancer and bone metastases who were younger than 70 years of age to see if radiotherapy extended their survival. They found that the 1-, 2-, 3-, 5-, 7- and 10-year survival rates showed no significant difference between a control group and those who had radiotherapy. They did find [...]

By | April 27th, 2016|Drugs & Treatments, Radiotherapy, Survival, Uncategorized|0 Comments
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