salvage therapy

Men Who Fail Primary Radiation Can Have Good Results After Salvage Surgery

Men who have decided to have radiation as their first (primary) treatment for prostate cancer have a one-third chance of recurrence. Some of those men have salvage radical prostatectomy (SRP)  to fight the recurrence.  A study shows this might be a good idea. Antoni Vilaseca, MD, etal from Memorial Sloan-Kettering Cancer Center in New York, studied 251 men who had a Salvage Radical Prostatectomy (SRP) after they failed their primary treatment with external beam radiation therapy, brachytherapy (seeds), or with both. The researchers evaluated long-term oncologic outcomes (survival and disease progression) of the SRP in general as well as evaluating if using minimally [...]

Salvage Radical Prostatectomy Improves Long Term Survival in Men with Radiation Recurrent Prostate Cancer

A retrospective study, using the SEER Date, a U.S. national database, analyzed data from men diagnosed with prostate cancer and found that salvage radical prostatectomy (SRP) improved the long-term survival in men whose cancer has returned after receiving radiation therapy. We know that approximately 30% of men who have radiation therapy as their primary therapy will have a recurrence of their prostate cancer within 5 years of completing the radiation. The researchers from the University of Missouri School of Medicine identified men with prostate cancer who underwent surgery after radiation. They identified and analyzed the overall and cancer-specific survival outcomes in 364 of these men who underwent salvage [...]

Positive Findings In Pelvic MRIs In Relapsed Prostate Cancer After Failed Radical Prostatectomy

There has been a lot of conversation about the role of and the use of multi-parametric MRIs in the initial diagnostic stages of prostate cancer, but little is known about its potential clinical application in the use of early salvage radiotherapy after failed radical prostatectomy. In a study to exam the potential of multi-parametric MRIs in men experiencing surgical failure as defined by a rising PSA post surgery, researchers reviewed the records and MRI studies of 70 men with rising PSA scores post surgery. They evaluated the incidence and location of recurrence based on pelvic multi-parametric MRI findings and to [...]

Comparing the Morbidity of HIFU to CYRO After Failed Radiation Therapy

Currently, there are a number of different treatments used to treat recurrent prostate cancer when the primary treatment had radiation has failed. In this situation surgery is considered very difficult and can only be successfully performed by an experienced surgeon, so alternative treatments are often considered. Long-term data about the success of these alternative treatments has not yet matured, however we do have some insight into the immediate morbidities caused by some of them. A group of researchers compared the morbidity of whole gland salvage ablation using cryotherapy (CRYO) as well as high-intensity focused ultrasound (HIFU) for radio recurrent prostate [...]