surgery

The Benefit of Using Local Prostate Cancer Therapy for Men with Lymph Node Positive Disease

In an issue of ONCOLOGY, there was a review of the literature provides us with a comprehensive review of the limited literature on management of men with prostate cancer who have pelvic lymph node involvement but no known distant metastatic disease at diagnosis. Common folklore has been that these men, with limited pelvic lymph node involvement, are considered “incurable” and managed solely with androgen deprivation therapy. However, there are several reasons to consider local treatment of men with lymph node positive prostate cancer with prostatectomy, radiation therapy, or both prostatectomy and radiation. Based on the literature we need to change [...]

Positive Findings In Pelvic MRIs In Relapsed Prostate Cancer After Failed Radical Prostatectomy

There has been a lot of conversation about the role of and the use of multi-parametric MRIs in the initial diagnostic stages of prostate cancer, but little is known about its potential clinical application in the use of early salvage radiotherapy after failed radical prostatectomy. In a study to exam the potential of multi-parametric MRIs in men experiencing surgical failure as defined by a rising PSA post surgery, researchers reviewed the records and MRI studies of 70 men with rising PSA scores post surgery. They evaluated the incidence and location of recurrence based on pelvic multi-parametric MRI findings and to [...]

Analyzing the Analysis – Is Surgery Superior to Radiotherapy? No, Despite the Results from A Large Canadian Study

It is a little out of the normal scope of this blog, but a recent prostate cancer study from Canada has received a lot of buzz and needs some commentary and analysis. The study concluded that for men who are diagnosed with local prostate cancer (still confined in the gland) live longer if they have surgery as opposed to radiation. Despite this conclusion, this study should not change anyone’s clinical course or decision making! This study was a meta-analysis of a lot of data from a lot of studies and on the face of its conclusions it should change clinical [...]

Comparing the Morbidity of HIFU to CYRO After Failed Radiation Therapy

Currently, there are a number of different treatments used to treat recurrent prostate cancer when the primary treatment had radiation has failed. In this situation surgery is considered very difficult and can only be successfully performed by an experienced surgeon, so alternative treatments are often considered. Long-term data about the success of these alternative treatments has not yet matured, however we do have some insight into the immediate morbidities caused by some of them. A group of researchers compared the morbidity of whole gland salvage ablation using cryotherapy (CRYO) as well as high-intensity focused ultrasound (HIFU) for radio recurrent prostate [...]

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