genetics

Did You Know That Metastatic Prostate Cancer Causes DNA Mutations?

Men with metastatic prostate cancer have higher rates of inherited gene mutations than men with non-metastatic prostate cancer.  Knowing about DNA mutations might help you make better treatment decisions. And you can also tell family members about their risk. Recent studies have shown that metastatic prostate cancer inherited mutations in the DNA-repair genes, such as the BRCA gene, can help guide treatment decisions as well as increase cancer risk in their family members. These mutations are more common in men with metastatic prostate cancer compared with men whose prostate cancer hasn’t spread outside the prostate gland. Men with advanced, metastatic prostate cancer should ask to be [...]

By | January 3rd, 2017|biomarkers, BRACA1, BRCA2, Genetic testing, genetics, Uncategorized|1 Comment

A New Genetic Test To Help You Understand Your Risk For A Prostate Cancer Recurrence

Base on a recently published news release, a prospective study performed and funded by the commercial company GenomeDx Biosciences showed that their new Decipher Cancer Classifier test reclassifies the tumor aggressiveness in men who have had surgery as their primary prostate cancer treatment. According to the company, this newly validated test will improve clinical decision-making following a radical prostatectomy. In this validation study, their Decipher Post-Op test was able to reclassified the tumor aggressiveness in a large number of men based on the genomic risk assessment as compared to our current clinical and pathological risk assessment tools. The company claims [...]

By | September 12th, 2016|Genetic testing, genetics, prognostic tools, Uncategorized|0 Comments

Understanding the Risk Factors for Hereditary Prostate Cancer – A Surprise

We often refer to prostate cancer as a family affair, or rather being passed on from father to son, etc. This is only partially true because there is still more prostate cancer diagnosed in men without any family history. For those cancers that are passed on from one family member to another it is important to understand the risks. This includes the risks for both being diagnosed and the risks for aggressiveness. It is generally accepted that if your brother has prostate cancer your risk of also having prostate cancer is doubled. But what does this really mean? Yes, you [...]

Myriad Genetics Attempts To Deny Patients Their Personal Genetic Information

 In 2013, Myriad Genetic failed – in a case that was heard in the United States Supreme Court - to patent the BRCA1 and BRCA2 genes.  We all have these two genes which, when they mutate, are associated with breast, ovarian and prostate cancers. If Myriad succeeded, they would have controlled patents on these genes and could establish a monopoly on all research and testing of these genes. Myriad is now facing a lawsuit over  denying their clients access to their own genetic information.  The four plaintiffs in the action underwent genetic testing with Myriad to determine their hereditary risk [...]