Multiple vs. One External Beam Radiation Dose for Palliation of Bone Pain in Men with Prostate Cancer

A man in the advanced prostate cancer online support group has asked, “Why the radiation (external beam to relieve bone pain from prostate cancer and to protect the bones from fractures) is given in so many "mini" doses rather than one or two larger doses. The answer is it doesn't necessarily have to be delivered in many smaller dosages. Guidelines from the American Society for Radiation Oncology (ASTRO) support treatment with a single fraction of radiation using a dose of 8 Gy to provide palliation for relief of pain from bone metastases in men with prostate cancer. Based upon a [...]