Choline C11

//Choline C11

18F-Fluciclovine PET/CT Superior to 11C-Choline PET/CT for the Detection of a Prostate Cancer Relapse

We have all been ever increasingly aware of the weakness of our scanning technologies when it comes to both diagnosing prostate cancer and its recurrence. Given that about 1/3 of all primary treatments for prostate cancer will fail and the cancer will return it is vital that we improve our ability to detect prostate cancer recurrences earlier. In recent years, there have been a few improved contrasts developed that have increased scanning sensitivity. Two competing contrasts are a new PET compound (anti-3-(18)F-FACBC or (18)F-fluciclovine) and (11)C-choline. Researchers set out to compare these two contrasts for their sensitivity to detect a [...]

Is There A Role For Surgery In Men With Nodal Oligometastatic Prostate Cancer After A Biochemical Failure?

Recently there have been a number of conversations in the prostate media around the topic of treating oligometastatic prostate cancer with a curative goal. Oligometastatic prostate cancer describes the disease state where primary treatment has failed as evidenced by an increasing PSA along with scanning evidence of a limited number of lymph nodes involved in and near to the prostate bed. Because of the development of better scanning technology and scanning contrasts more oligometastatic disease has been identified and so the conversation escalated about their treatment. The most commonly discussed treatments have involved radiation therapy. In a presentation at the [...]

Using choline-C11 PET/CT Scans To Predict Survival In Men With Recurrent Prostate Cancer

Choline-C11 PET/CT scans can identify the actual sites of recurrence of prostate cancer in men who have a rising PSA after receiving primary therapy. The question worth asking is if this type of scan might be able to be used for prognostic purposes. Knowing this might influence our treatment decisions as well as our basic life decisions. A retrospective analysis was performed of data from almost 200 men who had a radical prostatectomy as their primary prostate cancer treatment and who then received a choline PET/CT after a biochemical failure (PSA rising to a level greater than 0.2 mg/ml) while [...]

Choline C-11 A Second Shot To Halt The Cancer After Primary Treatment Failure

The dirty little secret that is kept from most of us when we receive primary treatment for prostate cancer is that there is a recurrence rate approaching 33%. This amazingly high rate is consistent no matter what primary treatment is elected. Radiation, surgery, HIFU the rates are the same, about 1/3 of us will experience a prostate cancer recurrence! Given this fact it is easy to understand the constant fear we live under when we finally understand the odds of having a recurrence. In the situation where we do have a recurrence the fear levels are notched even higher if [...]

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