CT Scans

//CT Scans

18F-Fluciclovine PET/CT Superior to 11C-Choline PET/CT for the Detection of a Prostate Cancer Relapse

We have all been ever increasingly aware of the weakness of our scanning technologies when it comes to both diagnosing prostate cancer and its recurrence. Given that about 1/3 of all primary treatments for prostate cancer will fail and the cancer will return it is vital that we improve our ability to detect prostate cancer recurrences earlier. In recent years, there have been a few improved contrasts developed that have increased scanning sensitivity. Two competing contrasts are a new PET compound (anti-3-(18)F-FACBC or (18)F-fluciclovine) and (11)C-choline. Researchers set out to compare these two contrasts for their sensitivity to detect a [...]

Predicting the Long-Term Survival of Men with A Biochemical Recurrence Post-Surgery Who Are Hormone Naive Can Change How We Treat Them

Appearing in the European Journal of Nuclear Medicine and Molecular Imaging a recent study provides data on the long-term survival of men with a biochemical recurrence after failed surgery. In the study by Giovacchini et al. it was shown that a PET/CT scan (specifically a [11C] choline PET/CT) could predict the long-term survival of men who are hormone-naive (not yet started ADT) who had a biochemical failure (where biochemical failure was defined by a PSA level > 0.2 ng/ml post surgery). The study was a retrospective analysis of  302 men who were hormone-naive and who had been previously treated with a [...]

Using CT Scans to Predict A Pending Spinal Cord Compression in Men With Castration-Resistant Prostate Cancer *

CT scans are often performed in the process of monitoring of advanced prostate cancer disease progression. One of the most serious impacts of advanced prostate cancer is spinal compression, which can lead to paralysis and significant pain. Being able to use the CT scan as a red flag warning about potential spinal cord compression could help a physician stay on top of this serious turn of events. In a study evaluating the CT scans potential to warn about a pending spinal cord compression 34 men with existing malignant spinal cord compression and who also had at least three prior CT [...]