A Brief Update of the Current Landscape of Bone Targeted Therapies for Prostate Cancer

Prostate cancer tends to metastasize to bones as opposed to soft tissue and other organs.   We have no idea why it does have a preference for bone, but it does. Developing bone metastases in prostrate cancer is a very strong negative prognostic indicator. Prostate cancer’s tendency to favor bone over soft tissue causes significant morbidity and mortality for men. Bone metastasis has a major impact on quality of life and longevity for men with prostate cancer and it needs to be aggressively treated. Because of this, prostate cancer survivors need to focus on drugs that slow down or interfere with [...]

Efficacy of Enzalutamide in Castrate-Resistant Prostate Cancer in Men with Visceral Metastases

We know that men with metastatic castration-resistant prostate cancer (mCRPC) and visceral metastases have a worse prognosis than those with non-visceral metastases. The important question we need to understand is what, of our currently available treatments, might be effective for this more aggressive and deadly type of prostate cancer? Results of the phase 3 AFFIRM clinical trial have demonstrated that treatment with the androgen receptor inhibitor enzalutamide (Xtandi) resulted in significant improvements in outcomes for men with mCRPC. This blog post discusses the efficacy of enzalutamide among men from the AFFIRM trial who had visceral disease. Men who were in [...]

To Debulk Or Not To Debulk, That Is The Question

You have been diagnosed with advanced or metastatic prostate cancer. It is a shock, you have cancer and your cancer has already spread outside of the prostate gland. Your doctor might have already told you that at this stage it is no longer curable, and technically it can be called terminal! That is a lot of stuff that has been just pushed on to your plate. Theoretically, this is correct, but for many of us, despite having this diagnosis, we will not die from the prostate cancer! Treatment today allows us to delay the cancer long enough that we will [...]

Improving Your Survival – Find the Right Hospital

Today’s New York Times (8/23/16) had an article written by Austin Frakt, which should be of interest to all of us with prostate cancer. The article, “Why It’s Crucial to Choose the Right Hospital appeared on page A3. The entire article is best described by the first sentence, “There’s an exceeding simple way to get better health care: Choose a better hospital.” The article dealt specifically with hospital death statistics over the last 20 years from heart attacks, but its conclusions should be the same for any serious illness including prostate cancer. In a study performed by health economists from [...]

By | August 23rd, 2016|General Information, Survival, Uncategorized|0 Comments
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