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Ask For a Blood test to identify AR-V7 in Circulating Tumor Cells if you are starting Xtandi or Zytiga

One of the hot topics in the prostate cancer community is the value of detecting AR-V7 tumor cells circulating in the blood. AR-V7 tumor cells in the blood predicts response or failure of treatment with enzalutamide (Xtandi) or abiraterone (Zytiga). A recent study found that men who have AR-V7 circulating tumor cells in their blood will not respond to Xtandi or Zytiga and will live longer if treated with a taxane based chemotherapy (docetaxel) regimen. A study in JAMA Oncology, showed that evaluating for the presence of circulating tumor cells (CTCs) with AR-V7 could optimize treatment protocols. The study looked at 161 men with progressing metastatic castration-resistant [...]

Men Who Fail Primary Radiation Can Have Good Results After Salvage Surgery

Men who have decided to have radiation as their first (primary) treatment for prostate cancer have a one-third chance of recurrence. Some of those men have salvage radical prostatectomy (SRP)  to fight the recurrence.  A study shows this might be a good idea. Antoni Vilaseca, MD, etal from Memorial Sloan-Kettering Cancer Center in New York, studied 251 men who had a Salvage Radical Prostatectomy (SRP) after they failed their primary treatment with external beam radiation therapy, brachytherapy (seeds), or with both. The researchers evaluated long-term oncologic outcomes (survival and disease progression) of the SRP in general as well as evaluating if using minimally [...]

Cancer Diagnosis Causes Increased Emotional Problems for Too Many of Us

Being diagnosed with cancer is tough. Being diagnosed with cancer is often coupled with clinically meaningful levels of mental or emotional distress. Researchers in Germany have found that during the prior four weeks nearly a third of more than 2,100 cancer survivors interviewed at inpatient and outpatient care centers experienced mental or emotional distress that meets the strict diagnostic criteria for mental disorders including anxiety, depressive and adjustment disorders. In the normal, non-cancer survivor population we would not expect to see rates higher than 18% at most. When the researchers evaluated the types of disorders they found that 11.5% of [...]

By | December 23rd, 2016|General Information, How We Live, mental health, Research, Uncategorized|0 Comments

Understanding the Confusion Around Drug Names

Drugs and their names are just confusing. When they are being developed they are given many different names. Despite their names the drugs (or treatments) are the same. Names are just names nothing more. For laymen, drugs having multiple names for the same drug is confusing. So, why are there so many different names for the same drug? Let me try and straighten out the confusion. Usually drugs, as they go through the development process, are given three different names; A chemical name that relates to its molecular composition. This chemical name is usually to long and complex to use [...]

By | December 15th, 2016|Drugs & Treatments, FDA, Uncategorized|0 Comments