Lethal Advanced Prostate Cancer Has Inherently Heterogeneity And Can Spread From Other Metastatic Sites

We still have a lot to learn about how prostate cancer actually spreads, or metastasizes. Current theory holds that the primary tumor is probably most responsible for the development of distant metastases. In a new genomic analysis of tissue performed at the Johns Hopkins University using tissue from prostate cancer patients this paradigm has been called into question. The genomic evidence shows that cells from other than the primary metastases also migrate to other body parts and form new sites of spread on their own. "The idea that metastatic tumors can seed and establish other metastatic tumors in patients is [...]

Liver Metastases and ECF – A Possible Treatment In A Not Good Situation

Liver metastases are uncommon in men with castrate resistant prostate cancer (CRPC). Having liver metastases is associated with more serious disease and shorter survival. How to treat men with liver metastases is still not very clear. It is felt that more active treatment might benefit these men. A standard regimen for treating gastric cancer is Epirubicin, Cisplatin and Flurouracil (ECF). This regimen has been reported to also have a response in CRPC in men with liver metastases. In a research survey of the use of ECF in CRPC was evaluated with the primary objective of determining its anti-tumor activity in [...]

Doctoral Student Develops A Device That Provides An Up-Close Look At Cancer’s Movement In The Body

Sometimes scientific research is amazing! We are so lucky to have so many brilliant and gifted young people interested in conquering cancer. One of these brilliant young people is a doctoral student at Johns Hopkins, Andrew Wong. Mr Wong is a Ph.D. student studying materials science and engineering. Along with his facility advisor he has developed a lab device that gives cancer researchers a microscopic look at metastasis. Ninety percent (90%) of cancer deaths are the result of spreading tumor cells or metastasis. We currently have very little understanding of this most lethal process that cancer uses to kill us. [...]

The Well Reviewed Guide to Advanced Prostate Cancer (A Survivor Perspective) Has Been Updated and is Now Available for a free Download

Somehow I have been negligent and not let people know that I have written and posted a major update of my “Guide to Advanced Prostate Cancer.” As in the past, it is available as a free download from the Malecare web site. Helping me to update the book was prostate cancer survivor Craig Pynn and my own caretaker, Wendy Lebowitz. Anyone reading the first edition will be surprised when you see how many changes and updates this edition has included. It now has a very extensive conversation about living in the world as a cancer survivor as well as more [...]

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