perineural invasion

The Well Reviewed Guide to Advanced Prostate Cancer (A Survivor Perspective) Has Been Updated and is Now Available for a free Download

Somehow I have been negligent and not let people know that I have written and posted a major update of my “Guide to Advanced Prostate Cancer.” As in the past, it is available as a free download from the Malecare web site. Helping me to update the book was prostate cancer survivor Craig Pynn and my own caretaker, Wendy Lebowitz. Anyone reading the first edition will be surprised when you see how many changes and updates this edition has included. It now has a very extensive conversation about living in the world as a cancer survivor as well as more [...]

Perineural Invasion – Is It An Accurate Predictor of Extra-Prostatic Extension of Prostate Cancer?

Many clinicians are concerned when a patient comes to them with prostate cancer that has been shown to have perineural invasion (PNI). PNI is defined as the presence of prostate cancer found by biopsy that tracks along or around a nerve within the perineural space. The presence of PNI has been a concern because of the possible relationship between the presence of perineural invasion and extra-prostatic extension (EPE) of prostate cancer. The neurons in question pierce the prostatic capsule and might allow easy exit of cancer cells from the gland into the capsule According to Gabriele Cozzi, MD who analyzed [...]