Advanced Prostate Cancer

Advanced Prostate Cancer/

For Our USA Readers: Office of Men’s Health Petition and Update

Our best chance for establishing an Office of Men's Health in the USA is now, in the early days of this new administration. Our Petition at whitehouse.gov is a first and important step.   Please sign and spread the word.  This effort is entirely up to us.  We can do this! Click and Sign here: http://bit.ly/2iWgnQG Here is the text of the petition: We petition for the establishment of an Office of Mens Health at the U.S. Department of Health and Human Services. This office would mirror the work of the existing Office of Womens Health, which has helped to [...]

By | January 23rd, 2017|advocacy, Politics of Cancer|0 Comments

Did You Know That Metastatic Prostate Cancer Causes DNA Mutations?

Men with metastatic prostate cancer have higher rates of inherited gene mutations than men with non-metastatic prostate cancer.  Knowing about DNA mutations might help you make better treatment decisions. And you can also tell family members about their risk. Recent studies have shown that metastatic prostate cancer inherited mutations in the DNA-repair genes, such as the BRCA gene, can help guide treatment decisions as well as increase cancer risk in their family members. These mutations are more common in men with metastatic prostate cancer compared with men whose prostate cancer hasn’t spread outside the prostate gland. Men with advanced, metastatic prostate cancer should ask to be [...]

By | January 3rd, 2017|biomarkers, BRACA1, BRCA2, Genetic testing, genetics, Uncategorized|1 Comment

Being A “Cancer Hater” is Not Productive

My wife Wendy periodically receives Facebook requests for her to “Hate Cancer.” Yes, she does hate cancer, but she wants us all to actually be productive about what we do with our “hate.” Wendy wrote on Facebook,  "I'm not a cut and paster, and certainly not a "hater," so I have an alternative suggestion.  I just had the remarkable experience of visiting the National Cancer Institute at NIH, when my husband (a survivor of 5 separate unrelated cancers, including one metastatic, and one very rare) volunteered for a clinical trial. The caliber of research and commitment there (and in so many of our [...]

By | December 30th, 2016|advocacy, Uncategorized|0 Comments

Ask For a Blood test to identify AR-V7 in Circulating Tumor Cells if you are starting Xtandi or Zytiga

One of the hot topics in the prostate cancer community is the value of detecting AR-V7 tumor cells circulating in the blood. AR-V7 tumor cells in the blood predicts response or failure of treatment with enzalutamide (Xtandi) or abiraterone (Zytiga). A recent study found that men who have AR-V7 circulating tumor cells in their blood will not respond to Xtandi or Zytiga and will live longer if treated with a taxane based chemotherapy (docetaxel) regimen. A study in JAMA Oncology, showed that evaluating for the presence of circulating tumor cells (CTCs) with AR-V7 could optimize treatment protocols. The study looked at 161 men with progressing metastatic castration-resistant [...]